Immunology research at UTSA and Texas Biomedical Research Institute includes research in autoimmune diseases, neuroinflammation, immunopathology, immunobiology, and immunotherapeutics.

Autoimmune disease occurs when the body's natural defense system fails to differentiate between its own cells and foreign cells, causing the body to mistakenly attack normal cells. The precise cause of autoimmune diseases is unknown.

Neuroinflammation is an inflammatory response of the nervous system that may be initiated in response to a variety of cues, including infection, traumatic brain injury, toxic metabolites, or autoimmunity.

Immunopathology is the study of disease outcomes due to debilitating immune response induced in response to infectious and non-infectious agents. Various animals models of infectious and non-infectious diseases are used to study immunopathology to better understand the progression and manifestation of human diseases.